Like RegClean, RegMaid will help you clean up your registry.
The Microsoft freeware can be downloaded from ftp://ftp.microsoft.com/Softlib/mslfiles/regmaid.exe.
Unlike RegClean, RegMaid has a GUI.
RegMaid provides four possible views:
CLSID - Resonably safe.
ProgId - Reasonably safe.
TypeLib - Only if you know for sure.
Interface - Only if you know for sure.
I always run RegClean before running RegMaid.
I always navigate to the RegMaid entries reported, using Regedt32, and only remove an entry that I understand and can't fix.