A: The focus for App-V 4.6 SP1 was the sequencing of applications, especially making the sequencing process easier and faster. It includes the new ability to use "package accelerators," which essentially allow an application to be sequenced by a few clicks in a wizard. Package accelerators can be used to sequence applications that include customizations that might be required to achieve the optimal sequence of an application. Going forward, expect application vendors to start providing these package accelerators to aid in the virtualization of their applications. Some package accelerators are available from Microsoft.
Also new to 4.6 SP1 is the ability to use a shared, read-only cache for Remote Desktop Services Session Hosts. Prior to SP1, the use of a shared, read-only cache was restricted to virtual desktop infrastructure (VDI) clients.
Sequencing the .NET Framework 4.0 isn't supported. Numerous other hotfixes have been rolled up into SP1.