JSI Tip 1912. How can I remove 'My Computer' from the desktop?

There is no standard Policy or registry entry to do this, but you can use brute force.

Use Regedt32 to navigate to:

HKEY_CLASSES_ROOT\CLSID\20D04FE0-3AEA-1069-A2D8-08002B30309D

On the Registry menu, choose Save Key, in case you change your mind. Then delete 20D04FE0-3AEA-1069-A2D8-08002B30309D and all its' subkeys.