In tip 2102 » What doesn't NTBackup backup/restore in Windows 2000?, we learned how to configure additional files not to backup, using the registry.
To configure additional files not to backup, using the GUI:
1. Run NTBackup.
2. On the Tools menu, press Options.
3. Select the Exclude Files tab.
4. Use the Add new, Edit, and Remove buttons in the All Users or specific user section to select the files not to backup.