A: Yes. MED-V runs a legacy client OS inside a virtual machine (VM) on a local PC. It's designed to run specific legacy applications that won't run on Windows 7 or to run websites that require Internet Explorer 6 (which runs inside the Windows XP MED-V VM). Because MED-V is running an OS, you should still have antivirus running inside the virtual OS. You might also need to make some exceptions on the host OS's antivirus to exclude the VHD file that contains the MED-V image, although this may vary based on the antivirus solution used.