In tip 0106, I described the DeleteRoamingCache registry value used to delete locally cached copies of roaming profiles.
If you are using Group Policy, you should enable the Delete cached copies of roaming profiles Group Policy instead:
1. Open the GPO you wish to modify, such as the Default Domain Policy. See tip 2893.
2. Navigate to Computer Configuration / Administrative Templates / System / Logon.
3. Double-click Delete cached copies of roaming profiles.
4. Press Enabled.
5. Press Apply.
NOTE: For Windows XP and later, navigate to Computer Configuration / Administrative Templates / System / User Profiles.
NOTE: This policy applies to computers. If you apply it to an OU (Organizational Unit), it applies to the computers in the OU, not to the users. If a user in an OU that has this policy, logs onto a computer in an OU that doesn't, a copy of the users roaming cache will remain on that computer.